Prestroke selective serotonin reuptake inhibitor use and functional outcomes after ischaemic stroke
نویسندگان
چکیده
منابع مشابه
Prestroke selective serotonin reuptake inhibitor use and functional outcomes after ischaemic stroke
Background Selective serotonin reuptake inhibitors (SSRIs) have been implicated in contributing to recovery after acute ischaemic stroke. In particular, poststroke initiation of an SSRI has been demonstrated to improve motor recovery. The role of prestroke SSRI use on functional outcomes and stroke recovery is less clear. We aimed to examine the effect of prestroke SSRI use on metrics of hospit...
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BACKGROUND AND PURPOSE Selective serotonin reuptake inhibitors (SSRIs) have been associated with an increased risk of bleeding but also a possible neuroprotective effect in stroke. We aimed to examine the implications of prestroke SSRI use in hemorrhagic and ischemic stroke. METHODS We conducted a registry-based propensity score-matched follow-up study among first-ever patients with hemorrhag...
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Background and Purpose The aim of the study was to investigate the efficacy and safety of the selective serotonin reuptake inhibitor citalopram in treating poststroke depression, since available treatments are usually poorly tolerated. Methods A 6-week double-blind, placebo-controlled trial was undertaken. Diagnosis and outcome were determined using the Hamilton Depression Scale, and unwanted e...
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Serotonin syndrome is a rare but potentially fatal adverse drug reaction associated with increased serotonergic activity in the central nervous system. It is characterized by a triad of symptoms, which include altered mental status, neuromuscular hyperactivity, and autonomic instability or hyperactivity. Due to the potential of rapid onset, it is important for clinicians to recognize the signs ...
متن کاملSelective serotonin reuptake inhibitors for stroke recovery.
CLINICAL QUESTION Are selective serotonin reuptake inhibitors (SSRIs) associated with better recovery after stroke? BOTTOM LINE SSRIs may be associated with improved recovery after stroke, even in persons without depression. However, much of the evidence is of poor quality. Large, high-quality trials are needed to evaluate the validity of the current evidence and improve precision of estimate...
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ژورنال
عنوان ژورنال: Stroke and Vascular Neurology
سال: 2018
ISSN: 2059-8688,2059-8696
DOI: 10.1136/svn-2017-000119